Projects and Collaborations of GermanVasc
GermanVasc was founded 2014 in Hamburg, Germany by C.-A. Behrendt (Head) and E. S. Debus. Various projects in health-care research and quality improvement have been coordinated by this growing academic working group. Over the years, GermanVasc has been served as founding member of international vascular collaborations as the International Consortium of Vascular Registries (ICVR) or the Medical Device Epidemiology Network (MDEpiNet). The group is deeply involved in the VASCUNET collaboration of the European Society for Vascular Surgery (ESVS). Under the project lead of C.-A. Behrendt, various projects in the field of data privacy compliant utilization of real-world data (registry data, health insurance claims data) in vascular research and quality improvement have been developed.
Behrendt CA
The Challenge of Data Privacy Compliant Registry Based Research
Behrendt CA
The Strengths and Limitations of Claims-based Research in Countries with Fee-for-Service Reimbursement
Recent publications
Behrendt CA, Debus ES, Schwaneberg T, Rieß HC, Dankhoff M, Makaloski V, Sedrakyan A, Kölbel T. Predictors of Bleeding or Anaemia requiring Transfusions in Complex Endovascular Aortic Repair and its Impact on Outcomes in Health Insurance Claims.
J Vasc Surg. 2019;In Press.
Behrendt CA, Sedrakyan A, Rieß HC, Heidemann F, Kölbel T, Debus ES. Short-term and long-term results of endovascular and open repair of abdominal aortic aneurysms in Germany. J Vasc Surg. 2017;66:1704-1711.e3
Stoberock K, Riess HC, Debus ES, Schwaneberg T, Kölbel T, Behrendt CA. Gender differences in abdominal aortic aneurysms in Germany using health insurance claims data. VASA. 2018;47:36-42.
Behrendt CA, Rieß HC, Schwaneberg T, Heidemann F, Tsilimparis N, Larena-Avellaneda A, Diener H, Kölbel T, Debus ES. Complex endovascular treatment of intact aortic aneurysms - An analysis of health insurance claims data. Gefässchirurgie. 2018;23(Suppl 1):32-38.
Behrendt CA, Sedrakyan A, Schwaneberg T, Kölbel T, Spanos K, Debus ES, Rieß HC. Impact of weekend treatment on short-term and long-term survival following urgent repair of ruptured aortic aneurysms in Germany. J Vasc Surg. 2018;69:792-799.e2.
Behrendt CA, Rieß HC, Schwaneberg T, Larena-Avellaneda A, Kölbel T, Tsilimparis N, Spanos K, Debus ES, Sedrakyan A. Incidence, predictors and outcomes of colonic ischaemia in abdominal aortic aneurysm repairs. Eur J Vasc Endovasc Surg. 2018;56:507-513.
Rieß HC, Debus ES, Schwaneberg T, Sedrakyan A, Kölbel T, Tsilimparis N, Larena-Avellaneda A, Behrendt CA. Gender disparities in fenestrated and branched endovascular aortic repair. Eur J Cardiothorac Surg. 2018;55:338-344.
Transatlantic Claims Study
GermanVasc is collaborating with the Department of Healthcare Policy and Research at the Weill Cornell College in New York City, USA. Under the project lead of C.-A. Behrendt, health insurance claims data is analysed to conduct comparative outcomes research in cardiovascular medicine.
The second largest health insurance provider, BARMER, and the third largest health insurance provider in Germany, DAK-Gesundheit, is supporting this scientific quality improvement project.
Highlights
Behrendt CA
International Consortium of Vascular Registries Consensus Recommendations for Peripheral Revascularization Registry Data Collection
Recent publications
Behrendt CA, Björck M, Schwaneberg T, Debus ES, Cronenwett J, Sigvant B. Recommendations for Registry Data Collection for Revascularisations of Acute Limb Ischaemia: a Delphi Consensus from the International Consortium of Vascular Registries.
Eur J Vasc Endovasc Surg. 2019;In Press.
Behrendt CA, Bertges D, Eldrup N, Beck AW, Mani K, Venermo M, Szeberin Z, Menyhei G, Thomson I, Heller G, Wigger P, Danielsson G, Galzerano G, Lopez C, Altreuther M, Sigvant B, Rieß HC, Sedrakyan A, Beiles B, Björck M, Boyle JR, Debus ES, Cronenwett J. International Consortium of Vascular Registries Consensus Recommendations for Peripheral Revascularization Registry Data Collection. Eur J Vasc Endovasc Surg. 2018;56:217-237.
ICVR
GermanVasc is founding member of the International Consortium of Vascular Registries (ICVR). The ICVR was launched in 2014 with the goal to establish a collaborative platform across registries to share data to improve the quality of vascular health care. Manuscripts regarding abdominal aortic aneurysms (AAA) and carotid artery stenosis were published by this collaboration recently. GermanVasc was coordinating an international modified Delphi-study to find a consensual agreement on minimal recommendations for PAD-registries.
Find the publication soon here!
Highlights
VASCUNET
Vascunet is a collaboration of vascular registries from Europe and Australasia, administered and partly funded by the European Society for Vascular Surgery (ESVS). It was founded in 1997 and several reports and eight original articles have been published so far. GermanVasc was recently coordinating an international comparison of amputation incidences for peripheral arterial disease and diabetes.
Find the publication soon here!
Highlights
Behrendt CA
International Variations in Amputation Practice - A VASCUNET Report
Rieß HC
Indicators of Outcome Quality in Peripheral Arterial Disease Revascularisations - A Delphi Expert Consensus
Behrendt CA
IDOMENEO – Does treatment reality in vascular medicine conform to guidelines and treatment?
IDOMENEO Consortium
In 2017, the IDOMENEO Consortium was established and funded (3,57 million Euros) by the German Federal Joint Committee (G-BA)
to implement a data privacy compliant and data safety registry plattform for peripheral vascular diseases in Germany. Central aspects of this multimethodological and multistage study is the utilization of health-insurance claims and primary registry data to perform quality improvement and vascular research.
Find the publications here!
Highlights
RABATT Consortium
Highlights
The RABATT study is a further development of the IDOMENEO study. RABATT aims to develop Big Data solutions and (deep) learning algorithms to be used in real-world-data. The study consortium will implement a risk score for patients with peripheral arterial disease (PAD) that can be used to predict the estimated course (e.g., amputation risk for endovascular versus open-surgical versus best-medical-treatment).
Find the publication soon here!
Recent publications
Schwaneberg T, Debus ES, Repgen T, Trute H, Müller T, Federrath H, Marschall U, Behrendt CA. [Development of a learning algorithm using real world evidence data - The RABATT study]. Gefässchirurgie. 2019;In Press.
Behrendt CA. [What is the reality behind real-world evidence?]. Gefässchirurgie. 2019;24:7-8.
Behrendt CA, Debus ES. [The limitations of randomization and the Medical Device Epidemiology Network (MDEPINET)]. Gefässchirurgie. 2019;In Press.
MDEpiNet
The Medical Device Epidemiology Network (MDEpiNet) is a global effort bringing together all parts of the medical device ecosystem to build a national medical device evaluation system. As a Public Private partnership, MDEpiNet is working to improve and integrate real-world data infrastructure, develop appropriate methodologies, and conduct studies to improve patient-centered outcomes for medical devices around the world. GermanVasc is founding member of this collaboration.
Find publications here!
Highlights
Vascular Research and Quality Improvement
Previous Projects of GermanVasc
Various regional and national projects have been coordinated by GermanVasc during the last years. The percutaneous infrainguinal stent (PSI) registry-study aimed to collate all percutaneous endovascular procedures for infrainguinal peripheral arterial occlusive disease (PAD) conducted in 74 German vascular centers between September and November 2015. The main aim of the PSI study was to obtain a realistic picture of percutaneous endovascular techniques used to treat suprapopliteal and infrapopliteal PAOD lesions and to describe the treatment procedures used by vascular specialists in Germany. The EQS study used consecutive registry data from the statutory population-based EQS-registry in Hamburg, covering all percutaneous endovascular revascularizations for PAD in the metropolitan area of Hamburg (5.3 million inhabitants). First projects cover radiation dosage and multidisciplinary team decisions. In 2015, the CORONA-study was started by GermanVasc. CORONA covers several methods and data sources to conduct quality improvement in vascular medicine. The DAK-study was initiated in 2016. GermanVasc conducts health-care research utilizing the DAK-database. Several publications have already been published or are currently under review.
Find the PSI-publication here!
Find the EQS-publication here!
Find the DAK-publication here!
Portfolio
GermanVasc is well-experienced in health-services research and quality improvement using real-world-data. GermanVasc is aiming to implement an independent scientific infrastructure in Germany to improve the utilization of primary registry data (GermanVasc-Platform) and health insurance claims data in the field of vascular diseases.
Real-World-Data | Big Data | Routine Data | Claims Data |
Registry Data | Mass Data | Administrative Data | Data Privacy |
BIG Claims | Registry Data | Real-World-Data
Recent Publications in Eur J Cardio-Thorac Surg | Bundesgesundheitsbl | VASA | J Vasc Surg
Chirurg | J Vasc Surg | Gefaesschirurgie
Ann Vasc Surg | Gefaesschirurgie | VASA | Eur J Vasc Endovasc Surg
Please find a complete list of publications here!